03246cmm a2200409 4500 214822400 TxAuBib 20120507120000.0 060322s2005||||||||||||||||||||||||eng|u 9781402037641 electronic bk. 1402037643 electronic bk. (OCoLC)65181548 N$T eng N$T OCLCQ YDXCP OCLCQ W2U OCLCQ GW5XE UV0 YNG EBLCP UAB CNTRU E7B MNU IDEBK AZU OCLCQ TUU OCLCQ TxAuBib Genome instability in cancer development [electronic resource] / edited by Erich A. Nigg. New York : Springer, 2005. 1 online resource (xv, 511 p.) : ill. (some col.) Advances in experimental medicine and biology ; 5, 5, 570, 570 Includes bibliographical references and index. The problem of genome instability. The multiplicity of mutations in human cancers / Ranga N. Venkatesan and Lawrence A. Loeb. Monitoring chromosome rearrangements / Michael R. Speicher -- DNA repair and mutagenesis. Nucleotide excision repair and its connection with cancer and ageing / Jaan-Olle Andressoo, Jan H.J. Hoeijmakers and Harm de Waard. DNA mismatch repair and colon cancer / Giancarlo Marra and Josef Jiricny. Base excision repair / Lisiane B. Meira, Nicholas E. Burgis and Leona D. Samson. Genomic instability in cancer development / Penny A. Jeggo. Translesion synthesis and error-prone polymerases / Catherine M. Green and Alan R. Lehmann -- Cell cycle progression and chromosome aberration. The INK4A/ARF network-cell cycle checkpoint or emergency brake? / Ana Gutierrez del Arroyo and Gordon Peters. DNA replication and genomic instability / Wenge Zhu, Tarek Abbas and Anindya Dutta. The dream of every chromosome: equal segregation for a healthy life of the host / Tomohiro Matsumoto and Mitsuhiro Yanagida. Telomere structural dynamics in genome integrity control and carcinogenesis / Roger A. Greenberg and K. Lenhard Rudolph. Gene amplification mechanisms / Michelle Debatisse and Bernard Malfoy. DNA methylation and cancer-associated genetic instability / Melanie Ehrlich. Deregulation of the centrosome cycle and the origin of chromosomal instability in cancer / Wilma L. Lingle, Kara Lukaswiewicz and Jeffrey L. Salisbury -- Genome integrity checkpoints. Mammalian DNA damage response pathway / Zhenkun Lou and Junjie Chen. ATM and cellular response to DNA damage / Martin F. Lavin ... [et al.] Mitotic checkpoint, aneuploidy and cancer / Tim J. Yen and Gary D. Kao. Cancer Genetic aspects. Genomics. Neoplasms genetics. Neoplasms etiology. Genomic Instability. Mutation. DNA repair. Biomedicine. Biomedicine general. Cancer Research. Cell Biology. Life Sciences, general. MEDICAL Oncology. HEALTH & FITNESS Diseases Cancer. Electronic books. Nigg, Erich A. Advances in experimental medicine and biology ; 5, 5, 570, 570. https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=150899 EBSCOhost